ENHANCED ANTI-TUMOR RESPONSE ELICITED BY A NOVEL ONCOLYTIC PSEUDORABIES VIRUS ENGINEERED WITH A PD-L1 INHIBITOR

Enhanced Anti-Tumor Response Elicited by a Novel Oncolytic Pseudorabies Virus Engineered with a PD-L1 Inhibitor

Oncolytic viruses combined with immunotherapy offer significant potential in tumor therapy.In this study, we engineered a further attenuated pseudorabies virus (PRV) vaccine strain that incorporates a PD-L1 inhibitor and demonstrated its promise as an oncolytic virus in tumor therapy.We first showed that the naturally attenuated PRV vaccine strain

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Correlation between aromatase expression in the eutopic endometrium of symptomatic patients and the presence of endometriosis

Hugo Maia Jr1,2, Clarice Haddad1,2, Julio Casoy11CEPARH, 2Itaigara Memorial Day Hospital, Salvador, Bahia, BrazilObjective: To investigate whether aromatase expression in the eutopic endometrium correlates with the presence and severity of endometriosis in patients with infertility and/or dysmenorrhea undergoing laparoscopy and hysteroscopy.Patient

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